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Unsurprisingly, Mark Twain (who was usually wrong about things, but cleverly so) loved it, but both Ruskin and Wilde, who were rather more familiar with the distinction between excellence and excess, did not

Time was categorised in 3-year periods (November 2006 to October 2009, etc.) to provide adequate sample sizes for this analysis

It is effective, and it is not addictive: antipsychotics produce no craving, no high and no compulsive use

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The objective of this study was to evaluate the prevalence of an association between smoking and primary headaches